integrated analysis for deep insights
approach
Our unique approach encompasses the analysis of whole blood to interrogate small RNA biomarkers from both the disease and host immune response. This is made possible by our AI-powered, highly sensitive, and robust mirCator platform that enables the discovery of small RNA signatures for precision medicine in various diseases. The resulting molecular blood tests look at all constituents of blood providing deep and often overlooked insights into health and disease.
mirCator: transforming small RNA analyses like Mercator’s projection transformed cartography
platform
Much like the Mercator projection changed cartography in the 16th century and enabled accurate maps of the world, our mirCator platform establishes the benchmark for analyzing and mapping small RNAs from blood.
The AI-powered platform opens the door to true precision medicine diagnostics. Taking process control to the next level, it covers the entire operational process from sampling to detection and data analysis, enabling early disease detection, therapy response prediction, and treatment monitoring.
- covers the entire operational process
- process control by extensive automation
- disease agnostic platform
- proprietary analytical innovations
- AI-based software solutions
sample collection
a streamlined collection protocol removes pre-analytical bias in processing
- no open pipetting
- immediate stabilization
- storage at -20°C
analyte extraction
an automated extraction process maximizes efficiency without compromising quality
- high yield RNA extraction
- optimized for small RNAs
- proprietary quality controls
blocking & detection
ultra-deep quantification of small RNA biomarkers on NGS platform
- blocking technology uncovers hidden, highly informative small RNAs
- digital PCR validation in single nucleotide resolution
RNA analytics
small RNA biomarkers reflect critical underlying biological processes and enable improved test performance
- precise quantification of known and previously unknown small RNAs
- analytical assay validation
unique insights
discovery of diagnostic biomarkers and signatures to power next-gen precision medicine platform
- leading small RNA blood biomarker database
- RNA identity revealed by cutting edge AI and ML
QC tracking
rigorous quality controls including proprietary spike-in RNAs
- extraction efficiency, RNA sample integrity, sequencing metrics, and RNA quantification
mirCator: quality-controlled from sample to insight
AI-based software solutions
AI
We have developed our own AI-powered suite of software for small RNA analysis that enhances analytic capabilities and minimizes quality and efficiency challenges.
Our key software innovations deliver:
- unprecented data insights
- minimal data loss
- maximum reproducibility
- unique cellular deconvolution approach
- functional target predictions for biological mechanisms
Classifynder, our proprietary software platform, supports versatile biomarker discovery using cutting-edge machine learning methods.
TransfoRNA, an artificial intelligence-powered small RNA annotation tool that leverages language models to annotate sequences.
miR-Blood small RNA atlas & database
atlas
Our miR-Blood atlas is a published high-quality small RNA expression database for the key components of human peripheral blood. The ultra-deep expression profiling of plasma and ten purified cell-type populations provides insights into the source of origin of blood-based small RNAs to further our understanding of blood and immune biology.
This high-quality resource is freely available to explore via our interactive miR-Blood dashboard at
