Explore our discovery platform

Technology

Our novel small RNA discovery platform is applicable to oncological, neurological, cardiovascular & autoimmune diseases.

Our combination of deep machine learning expertise with equally deep biological validation has led to the development of ground-breaking diagnostics in our first two clinical applications.


 

Why small RNA

Small RNAs

Small RNAs are small, highly conserved, non-coding RNAs playing crucial roles in the regulation of virtually all aspects of living cells.

Small RNAs have been implicated in a wide range of diseases including different types of cancers, heart conditions and neurological diseases. They are promising candidates for diagnostic and prognostic biomarkers, as well as predictors of drug response. As non- or minimally invasive biomarkers from body fluids, they show a remarkable extracellular stability making them near ideal clinical biomarkers.

Collection


  • Minimally invasive
  • Patient friendly & reproductible
  • Sample stable for storage & transport

Measurement


  • Standard platforms
  • High throughput
  • Quantitative
  • Cost-efficient

Dynamics


  • Dynamic regulator of cell/tissue function
  • Monitors physiology and/or pathology in real time
  • Longitudinal monitor

Specificity


  • Multiple markers
  • Baseline steady in time
  • Unaffected by other unrelated physiology e.g. exercise

Application


  • Multiple diseases
  • Primary diagnosis
  • Disease/treatment monitoring
  • Companion diagnostics

Insight


  • Origin of disease
  • Immunological response
  • Immune status

Harnessing the predictive power of blood-borne SMALL RNAs