Developing novel miRNA diagnostics to improve human health

What drives us

Earlier, More Accurate Detection Saves Lives

We are pioneering the development of novel miRNA-based blood borne diagnostics for early disease detection of a broad range of indications.

Improving patient treatment

We have developed a best-in-class blood based complementary diagnostic for the selection of late-stage NSCLC patients most likely to benefit from immunotherapies with the goal of delivering immediate value and actionable clinical guidance.

Explore Hummingbird’s DiagnosticS pipeline for multiple diseases

Diagnostics Pipeline

Broad pipeline of proprietary, miRNA-based diagnostic tests from blood.

miRisk

PREDICTION OF RESPONSE TO IMMUNOTHERAPY

•Blood-based microRNA panel that predicts immunotherapy response in stage IV NSCLC

•Significant and improved survival prediction (better than PD-L1 staining)

•Significant and immediate value for patients

miLung

EARLY DETECTION OF LUNG CANCER

•Blood-based microRNA panel that detects early-stage NSCLC

•Best performance reported from a blood test for early-stage lung cancer

Tackling unmet medical needs

Explore HumminGbird’s Pharma service options

PRODUCTS

With a track record of more than 7 000 clinical blood samples measured in more than 15 diseases thereof 2 500 only in lung cancer, hummingbird has developed best-in-class expertise in processing and analyzing blood-borne miRNAs, evaluating the immune system‘s response to disease.

EXTRACTION SERVICES

non-invasive sample sources as key for early disease detection & therapeutic monitoring
body fluids, including whole blood, serum, plasma, CSF, urine
optimized and validated protocols

MICROARRAY SERVICES

Agilent Certified Service Provider
latest miRBase content
from customer consultation to analysis in 4-6 weeks
Services include:
- project consulting
- quality control of incoming samples
- miRNA profiling
- bioinformatic analysis

PANEL SERVICES

disease-related miRNA panels with targeted content
rapid analysis of disease relevant miRNAs
carefully-curated collection of disease-related miRNAs
more streamlined experiments
non-invasive miRNA biomarker studies

VALIDATION SERVICES

validation & quantitative analysis of biomarker candidates
services on different validation platforms:
- HT-qRT-PCR for big cohorts
- multi-bead flowcytometry for small to intermediate no. of biomarkers per signature
- qRT PCR for small no. of biomarkers per signature

BIOINFORMATICS SERVICES

statistical analysis & biomarker signature development
bioinformatics report
- background correction and normalization
- differential expression analysis
- contextual, integrative analysis of differentially expressed biomarker candidates
- multivariate, combined analysis of different biomarker classes

HBDx@clinic

miRCollect
Blood Collection Kit

For measurement of miRNA signatures from venous blood