publications

TransfoRNA: Navigating the Uncertainties of Small RNA Annotation with an Adaptive Machine Learning Strategy
Taha Y, Jehn J, Kahraman M, Frank M, Heuvelman M, et al.
bioRxiv 2024

miR-Blood – a small RNA atlas of human blood components
Jehn J, Trudzinski F, Horos R, Schenz J, Uhle F, et al.
Scientific Data 2024

Early Detection of Lung Cancer using small RNAs
Sikosek T, Horos R, Trudzinski F, Jehn J, Frank M, et al.
Journal of Thoracic Oncology 2023

A blood-based miRNA complementary diagnostic predicts immunotherapy efficacy in advanced stage NSCLC with PD-L1 TPS ≥50%
Rajakumar T, Horos R, Kittner P, Kahraman M, Sikosek T, et al.
Journal of Thoracic Oncology Clinical and Research Reports 2022

A blood-based miRNA signature with prognostic value for overall survival in advanced stage non-small cell lung cancer treated with immunotherapy
Rajakumar T, Horos R, Jehn J, Schenz J, Muley T, et al.
npj Precision Oncology 2022

LP48- Early Detection of Alzheimer's Disease Using microRNAs
Steinkraus B, Heuvelman M, Cummings JL, Manson J, Ritchie C
JPAD The Journal of Prevention of Alzheimer's Disease 2022

Toward the blood-borne miRNome of human diseases
Keller A, Leidinger P, Bauer A, ElSharawy A, Haas J, et al.
J Nature Methods 2011

Temporal- and Strain-Specific Host MicroRNA Molecular Signatures Associated with Swine-Origin H1N1 and Avian-Origin H7N7 Influenza A Virus Infection
Loveday E-K, Svinti V, Diederich S, Pasick J, Jean F
J Virol. 2012

Relevance of pre-analytical blood management on the emerging cardiovascular protein biomarkers TWEAK and HMGB1 and on miRNA serum and plasma profiling
Basso D, Padoan A, Laufer T, Aneloni V, Moz S, et al.
Clin Biochem. 2017

PDAC-derived exosomes enrich the microenvironment in MDSCs in a SMAD4-dependent manner through a new calcium related axis
Basso D, Gnatta E, Padoan A, Fogar P, Furlanello S, et al.
Oncotarget 2017

Circulating microRNA profiling in patients with advanced non-squamous NSCLC receiving bevacizumab/erlotinib followed by platinum-based chemotherapy at progression (SAKK 19/05)
Joerger M, Baty F, Früh M, Droege C, Stahel RA, Betticher DC, von Moos R, Ochsenbein A, Pless M, Gautschi O, Rothschild S, Brauchli P, Klingbiel D, Zappa F, Brutsche M
Lung Cancer 2014

Ultra deep sequencing of Listeria monocytogenes sRNA transcriptome revealed new antisense RNAs
Behrens S, Widder S, Mannala GK, Qing X, Madhugiri R, Kefer N, Abu Mraheil M, Rattei T, Hain T
PloS ONE 2014

miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis.
Coskun M, Bjerrum JT, Seidelin JB, Troelsen JT, Olsen J, et al.
World J Gastroenterol. 2013

Low Levels of Cell-Free Circulating miR-361-3p and miR-625* as Blood-Based Markers for Discriminating Malignant from Benign Lung Tumors
Roth C, Stückrath I, Pantel K, Izbicki JR, Tachezy M, et al.
PLoS One. 2012

microRNA Response to Listeria monocytogenes Infection in Epithelial Cells
Izar B, Mannala GK, Mraheil MA, Chakraborty T, Hain T
Int J Mol Sci. 2012

Circulating micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection
Schrauder MG, Strick R, Schulz-Wendtland R, Strissel P, Kahmann L, et al.
PloS ONE 2012

Micro-array profiling exhibits remarkable intra-individual stability of human platelet micro-RNA
Stratz C, Nührenberg TG, Binder H, Valina CM, Trenk D, et al.
Thromb Haemost. 2012

Microfluidic primer extension assay
Beier M, Boisguérin V
Methods Mol Biol. 2012

MiRNA expression patterns predict survival in glioblastoma
Niyazi M, Zehentmayr F, Niemöller OM, Eigenbrod S, Kretschmar H, et al.
Radiat Oncol. 2011

Cause and Effect
Amarantos I, Laufer T, Brefort T
EBR 2011

MicroRNA profiling during cardiomyocyte-specific differentiation of murine embryonic stem cells based on two different miRNA array platforms
Gan L, Schwengberg S, Denecke B
PLoS One 2011

Circulating microRNAs in patients with coronary artery disease
Fichtlscherer S, De Rosa S, Fox H, Schwietz T, Fischer A, et al.
Circ. Res. 2011

Heptahelical receptors GprC and GprD of Aspergillus fumigatus are essential regulators of colony growth, hyphal morphogenesis and virulence
Gehrke A, Heinekamp T, Jacobsen DI and Brakhage AA
Appl. Envir. Microbiol. 2010

ArcS is the cognate sensor kinase in an atypical Arc system of Shewanella oneidensis MR-1
Lassak J, Henche A, Binnenkade L and Thormann KM
Appl. Envir. Microbiol. 2010

Characterization of the Zoarces viviparus liver transcriptome using massively parallel pyrosequencing.
Kristiansson E, Asker N, Forlin L and Larsson DG
BMC Genomics 2009

Pharmaceutical Industry Effluent Diluted 1:500 Affects Global Gene Expression, Cytochrome P4501A Activity and Plasma Phosphate in Fish
Gunnarsson L, Kristiansson E, Rutgersson C, Sturve J, Fick J, et al.
Environ Toxicol Chem. 2009

Intimate bacterial–fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans
Schroeckh V, Scherlach K, Nützmann HW, Shelest E, Schmidt-Heck W, et al.
PNAS 2009

Microfluidic-based enzymatic on-chip labeling of miRNAs
Vorwerk S, Ganter K, Cheng Y, Hoheisel J, Stähler PF and Beier M
New Biotechnology 2008

Small Molecules with Big Impact in Cancer
Beier V, Hoheisel J
BIOforum Europe 2008

Gene expression in Fusarium graminearum grown on plant cell wall
Carapito R, Hatsch D, Vorwerk S, Petkovski E, Jeltsch JM and Phalip V
Fungal Genet. Biol. 2008

A flexible and fully integrated system for amplification, detection and genotyping of genomic DNA targets based on microfluidic oligonucleotide arrays
Summerer D, Hevroni D, Jain A, Oldenburger A, Parker J et al.
New Biotechnology 2008

Arrayed primer extension on in situ synthesized 5´-3´- oligonucleotides in microchannels
Pullat J, Kusnezow W, Jaakson K, Beier M, Hoheisel JD and Metspalu A
New Biotechnology 2008

Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples
Pullat J, Fleischer R, Becker N, Beier M, Metspalu A and Hoheisel JD
BMC Genomics 2007

Mit der Geniom-Microarray-Technologie HPV-Genotypen auf der Spur
Schliwka J, Pullat J, Devilliers EM, Hoheisel JD and Beier M
BIOspektrum 2007

Transcription analysis using high-density micro- arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol
Mogensen J, Nielsen HB, Hofmann G and Nielsen J
Fungal Genet. Biol. 2006

OligoWiz 2.0 – integrating sequence feature annotation into the design of microarray probes
Wernersson R and Nielsen HB
Nucleic Acids Res. 2005

New weakly expressed cell cycle-regulated genes in yeast
de Lichtenberg U, Wernersson R, Jensen TS, Nielsen HB, Fausbøll A et al.
Yeast 2005

Alternative splicing microarrays reveal functional expression of neuron-specific regulators in Hodkin lymphoma cells
Relógio A, Ben-Dov C, Baum M, Ruggiu M, Gemund C et al.
J. Biol. Chem. 2005

Characterization of an Escherichia coli elaC deletion mutant
Schilling O, Rüggeberg S, Vogel A, Rittner N, Weichert S et al.
Biochem. Biophys. Res. Commun. 2004

Validation of a novel, fully integrated and flexible microarray benchtop facility for gene expression profiling
Baum M, Bielau S, Rittner N, Schmid K, Eggelbusch K et al.
Nucleic Acids Res. 2003